nucleotide

['nju:kliətaid]

n. 核苷酸

词形变化：

形容词: nu-cleosomal |

n.

【生化】核苷酸

nucleotide

词形变化：

形容词: nu-cleosomal |

nucleotide['nju:kliətaid; -tid]n.1.■【生物化学】核苷酸

1. (Biochemistry)a compound consisting of a nucleoside linked to a phosphate group. Nucleotides form the basic structural unit of nucleic acids such as DNA
   (生化)核苷酸
   

nucleotide

名词 nucleotide:

a phosphoric ester of a nucleoside; the basic structural unit of nucleic acids (DNA or RNA)

nucleotide

■Nucleotide diversity in these 4 populations was Dai 1.52, Wa 1.38, Lahu 1.31and Tibetan 1.40 respectively.

4个群体的核酸多态度分别为傣族1.52，佤族1-38，拉祜1.31，藏族1.40，总多态度为1.39。

■The second nucleotide in optimal human CpG motifs was thymidine, while in less active human CpG motifs or optimal murine CpG motifs, it was purines.

5′ GTCGTT 3′和 5′ GTCGTC 3′ 2个基序对人B细胞有高度免疫刺激活性 ,第二位碱基均为“T” ,而在小鼠CpG基序中该位碱基为“G”或“A”。

■Eight cases have mutation from adenine (A) to cytosine (C) in 546th nucleotide and from asparagine (N) to threonine (T) in 131st amino acid residue.

8份序列均存在第546位核营酸从A到C的突变，使第131位氨基酸由天冬氨酞(N)变为苏氨酸(T)。

■There are big differences in the nucleotide and amino acid sequences of envelope, NS1 gene between B strain and NGC strain.

B株E、NS1基因序列和氨基酸序列与NGC株存在差异 ;

■The human CYP2B6 gene is highly polymorphic,having many single nucleotide polymorphisms in promoters and coding regions.

CYP2B6具有高度基因多态性,在基因编码区和非编码存在许多单碱基突变。

■The whole nucleotide sequence of D2V-HN89 envelope gene was 1? 464bp. Nucleotide and amino acid homology were 95% and 98% respectively between D2V-HN89 and D2V-NGC.

D2V HN89株E基因核苷酸全长 146 4bp ,核苷酸和氨基酸序列与D2V NGC株的同源性分别为 95%和 98%,系统树分析显示其与登革 2型牙买加株及登革 2型巴西 90株的亲缘关系最近。

■The information inside a DNA molecule is encoded by the nucleotide bases adenine, thymine, guanine and cytosine (A, T, G and C).

DNA分子携带的资讯是由核苷酸碱基腺嘌呤（A）、胸腺嘧啶（T）、鸟嘌呤（G）及胞嘧啶（C）所编写。

■DNA is extremely well suited to making such derivatives because every nucleotide along the helix has sites where molecules can be attached.

DNA极适合用来制造这些衍生物，因为DNA螺旋上的每一个核苷酸，都有许多位置可以接上外来分子。

■DNA examination identified a missense mutation at nucleotide 134 of exon 5 of the SOD1 gene resulting in the aminoacid substitution serine-134-asparagine (S134N).

DNA检查确定了SOD1基因第5外显子的第134位核苷酸的错义突变，导致了第134位的氨基酸由丝氨酸替换为天冬酰胺酸。

■LA strain had the highest nucleotide sequence similarity with WFL strain, as high as 96%, and LA strain also belonged to topotype Cathay, serotype O.

LA株与WFL株核苷酸序列相似性最高，达96%，也属于O型的Cathay型毒株。

■The NCBI taxonomy database contains the names of all organisms that are represented in the genetic databases with at least one nucleotide or protein sequence.

NCBI的分类学数据库包括所有遗传数据库里的生物体，这些数据至少含有一种核苷酸或蛋白质序列。

■The ORF encoding p10 was 261 nucleotide long and encoding a putative 87 amino acid polypeptide of 9.3 kD.

P10基因编码区全长261bp，可编码分子量为9.3kD，由87个氨基酸残基组成的多肽。

■There was high degree of homology in nucleotide sequence between the PCR expandedATCC 10031 acrAB gene sections and the corresponding ones in Escherichia coli.

PCR扩增的 ATCC 10031的 acrAB基因片段同大肠埃希菌acrAB基因相应片段,在核苷 序列上具有很高的同源性。

■A Single Nucleotide Polymorphism in the MDM2 Promoter Attenuates the p53 Tumor Suppressor Pathway and Accelerates Tumor Formation in Humans.

pdf本站所有图书及资料均可在子午学术论坛得到应助下载。

■PCR-SSCP technique is an important method in Single nucleotide polymorphism analysis .

SSCP是单核苷酸多态性分析的一项重要技术。

■SZ strain had the highest nucleotide sequence similarity with Tau-YuanTW97 strain, as high as 93%, so SZ strain should be classified to topotype Cathay, serotype O.

SZ株与Tau-YuanTW97株核苷酸序列相似性最高，达93%，属于O型的Cathay型毒株；

■UDP stands for Uridine-diphosphate, a phosphorilated derivative of the nucleotide Uridine found in RNA (not DNA).

UDP对尿苷二磷酸的立场，磷酸化核苷衍生物。在RNA（不是DNA）中发现尿苷。

■Ls-rRNA 5' nucleotide sequence of Rohdea japonica (Liliaceae) and its evolutionary significance.

万年青 Ls-rRNA 5' 端核苷酸序列及进化意义.

■The recombinantpGEX-T-HEV has been successfully constructed, and HEV nucleotide of whichwas 92.9% homologous with that of the Burma strain of HEV (ET1.l).

与HEV缅甸株ET1.1的核苷酸序列比较，同源性为92.9%。 三、pGEX-4T-3-HEV重组体在大肠杆菌中的表达

■Nucleotide similarities between the S1 gene of AVAV C-98 and that of ARV-176,MDRV-YJL,ARV-S1133 and ARV-138 were 99.9%,99.3%,97.9% and 81.2%,respectively.

与MDRV-YJL的同源性为99.3%,与弱毒疫苗株ARV-S1133的同源性也达97.9%; 与ARV-138株的同源性最低,为81.2%。

■By comparing with the published genomic sequence of AEV vaccine strain 1 143,there are 98% nucleotide and 97.6% amino acid identities between them.

与已发表的AEV疫苗株1143的基因组序列比较发现,它们之间核苷酸和氨基酸的同源性分别为98%和97 6%。

■The nucleotide differences are9.7% between pADR-1 and ayw,9.3% between pADR-1 and adw,while therestill is about 2% dieffrence between pADR-1 and pHBr330 reported by Ono.

与已报道的ayw和adw亚型HBV DNA的核苷酸顺序差异较大,分别为9.7%和9.3%。

■The DLA EIAV gag shared the homology of 80% in nucleotide and 84.47% in amino acid with the EIAV Wyoming 1369 strain.

与美国EIAVWyoming 136 9株比较 ,核苷酸同源性为 80% ,氨基酸同源性为 84 47%。

■However, between two isolated strong virulent strains, there was a low homogeneity of 88.2% in nucleotide, and there was a high homogeneity of 93.9% in amino acid residue.

两分离株核苷酸序列同源性较低,为88.2%,但氨基酸序列同源性较高,为93.9%。

■A full-length cDNA of DFL and its antisense nucleotide sequence have been transformed into Nicotiana tabacum under the control of a cauliflower mosaic virus 35S promoter.

为了鉴定DFL基因的功能作用,构建了由35S启动DFL基因的正反义表达载体(载体中同时包含有由另外两个35S启动的潮霉素筛选基因和GUS组织化学染色基因)转化烟草。

■Software solution that provides a visual interface to nucleotide mutations.

为核甘酸突变提供视觉介面的软件解决方案。

■Principal constituent: Nucleotide, linolenic acid, linoleic acid, skimmed milk, lactose, lactalbumin, ingredients and so on mineral substance, Vitamin, taurine.

主要成分：核苷酸、亚麻酸、亚油酸、脱脂奶，乳糖，乳清蛋白，矿物质、维生素、氨基乙磺酸等成分。

■Adenosylcobalamin (coenzyme B12), for example, contains an entire RNA nucleotide, and thiamine pyrophosphate (coenzyme B1) carries around a piece of sugar-phosphate backbone.

举例来说，维生素B12腺酶钴胺（adenosylcobalamin）含有一个完整的RNA腺酶酸；

■A nucleotide molecule that consists of a combination of two nucleotide units.

二核苷酸两个单核苷酸结合而成的核苷酸分子

■The ionotrophic nucleotide receptor P2X(7) regulates compartmentalized acute inflammation and the immune response to airway pathogens.

亲离子性核苷酸受体P2X(7)调节划分急性炎症的局限化和对气道病原体的免疫反应。

■Most genetic differences in people probably take the form of single nucleotide polymorphisms, or SNPs (pronounced “snips”), in which a single DNA letter substitutes for another.

人与人之间多数的基因差异，是以单核苷酸多型性（SNP）的形式出现；那是DNA上单一个碱基遭到替换所造成的。

■Furthermore,DNA was also found to be made of nucleotide chains made of four bases,commonly represented by A,C,T,and G.

人们还发现，DNA由核苷酸链组成，而组成核苷酸链的是四种碱基，通常用A、C、T和G来代表。

■Using high-density genomewide single nucleotide polymorphism (SNP) genotyping arrays, they identified a genetic locus associated with the disease.

他们使用高密度基因组单核苷酸多态性(SNP)基因序列方法，辨识与此病症有关的基因位置；

■They then confirmed 30 suspected single nucleotide polymorphisms (SNPs) in nearly 22,000 women with breast cancer and a similar number of controls spanning 22 studies.

他们在横跨22项研究将近22，000名乳腺癌女性和基本相同数目的对照妇女中发现了30个可疑的单核苷酸多态性位点。

■His work showed that the inability to add nucleotide repeats to chromosomes led to telomere shortening and eventually cell death.

他的研究表明向染色体中添加核苷酸重复并不会导致端粒减短及最终的细胞死亡。

■Classically, the nucleotide sequence in DNA has been considered as the sole driver of heredity.

传统遗传学认为，DNA的核苷酸序列是遗传的唯一基础。

■However, no difference in t he nucleotide sequence of these exons was detected in all these selected PV pati ents who had different ...

但从我们选取的对维甲酸反应性不同的寻常型银屑病患者中,未发现彼此间外显子碱基序列存在差异。

■But if the patients have cirrhosis, which means severe disease, then what we generally do is do not stop nucleoside or nucleotide analogue.

但是如果患者有肝硬化，这种严重的疾病时候，我们一般所要做的都是不要停止核苷酸或者核苷类似物等药物。

■You mean combination therapy or monotherapy? Nucleotide analogue with interferon combination?

你说的是联合治疗或者单药治疗吗？核苷类似物联合还是和干扰素联合？

■The complate nucleotide sequences of the cloned preS genes(preS-HZ and preS-LZ,GenBank accession numbers:Af325674 and AF325675 respectively) were 522bp long,encoding 174aa.

克隆的HBVpreS基因杭州分离物 (preS HZ)和兰州分离物 (preS LZ)全长 5 2 2个核苷酸 ,编码174个氨基酸。

■The holoenzyme recognizes specific nucleotide sequences on the DNA duplex(promoters).

全酶还能识别DNA双链分子上的特定核苷酸序列（起动基因）。

■In all of these samples there were 69 nucleotide variations and 67 haplo-types. There was 2.679 mutation sites on average per person.

共发现69个位点变异,平均每个个体存在2.679个碱基突变,检出67个单倍型,基因多样性为97.92%。

■The record of EST database is more than 120,000.2. Nucleotide Sequences Extension System in silico (NSES) has been established.

其中,家蚕的:EST’数据库中的记录量超过了12万。2.建立了核酸序列电子自动延伸系统。

■It had highest homologies with two isolates from Hangzhou,HZLB1 and HZLB2,which amounted to 98.7% and 99.0% at nucleotide level and 99.0% and 99.7% at amino acid level.

其中与中国浙江杭州萝卜的两个分离物HZLB1、HZLB2同源性最高,核苷酸序列的同源性为98.7%和99.0%,氨基酸序列同源性为99.0%和99.7%。

■The homology of Giardia canis virus to sequence of L13218(GenBank) was 94.62% in the nucleotide,and 93.50% in the amino acid levels.

其序列与国外报道的人源蓝氏贾第虫病毒(L13218)序列同源性为94.62%,编码的氨基酸同源性为93.50%;

■It contains abundant dainty substances as nucleotide, guanylic acid, inosinic acid, polypeptide and amino acid, as well as plenty of vitamin B complex.

其核苷酸、鸟甘酸、肌苷酸及多肽和氨基酸等美味物质异常丰富，还含有大量的维生素B群。

■FCY1 strain has more high divergence than WLD1.The difference of nucleotide sequence of the hly gene has not relationship with its trgion and source.

分离菌株WLD1和FCY1,尤其是FCY1分化程度较高,Lmhly基因核苷酸序列差异的距离与地理分布、菌株的样品来源无相关性。

■The effects of adding mixture nucleotide (MN) on the micellization of DgP in aqueous, solution were studied by turbidimetry, differential scanning calorimetry (DSC) and DLS.

利用浊度法、示差扫描量热法(DSC)和动态光散射研究了外加混合核苷酸(MN)对于DgP水溶液胶束化行为的影响。

■SNPs: Single Nucleotide Polymorphisms. (Image courtesy of the U.S. Department of Energy Human Genome Program.

单核甘酸变异。(影像提供:美国能源部人类基因组计划。

■Single nucleotide polymorphisms (SNPs), the third-generation genetic marker, possess the characteristic of large numbers and dispersed distribution.

单核苷酸多态(Single-nucleotide polymorphism，SNP)作为第三代遗传标记，具有数量大，分布广的特点。