oncogene

['ɔŋkədʒi:n]

n. 致癌基因

n.

【医】致癌基因

oncogene

oncogene['ɔŋkədʒi:n]n.1.■【生物学】致肿瘤基因，致癌基因

1. (Medicine)a gene which in certain circumstances can transform a cell into a tumour cell
   (医)致癌基因
   

oncogene

名词 oncogene:

a gene that causes normal cells to change into cancerous tumor cells

同义词：transforming gene

oncogene

■Keywords bcl 2 oncogene;antisense oligodeoxynucleotide;drug design;leukemia cell;

2基因;反义核酸;药物设计;白血病细胞;

■Detection of ras oncogene product-P_(21)protein in human bladder transitional cell carcinoma with ABC immunoelectrophoresis

ABC免疫电泳对膀胱癌P_（21）蛋白表达的观察

■The anaplastic lymphoma kinase (ALK) is the oncogene of most anaplastic large cell lymphomas (ALCL), driving transformation through many molecular mechanisms.

ALK是大部分间变性大细胞淋巴瘤（ALCL）的癌基因，它通过很多分子机制促进变异。

■Expression of Bcl-2/Bax Oncogene Protein in Acoustic Neuroma Tissues and Its Significance

Bcl-2及Bax基因蛋白在听神经瘤组织中的表达及意义

■bcr/abl oncogene

bcr／abl融合癌基因

■Bcl-2 oncogene protein

Bel-2

■Mutational activation of the BRAF oncogene is the most common genetic alteration in cutaneous melanoma.

BRAF癌基因突变的激活是皮肤黑色素瘤最常见的基因改变。

■The product of proto oncogene c Cbl has been proved as a new ubiquitin ligase (E3) of RING finger type for ubiquitin proteasome pathway.

c Cbl最近被证明是泛素 蛋白酶体 (ubiquitin proteasome)通路中的一个新的RINGFinger型泛素连接酶 (ubiquitinligase ,E3) .

■The study of abnormal activating mechanism of c-fms oncogene and antisense c-fms bearing AFP enhancer with hepatocellular carcinoma

c-fms癌基因异常激活机制及携带AFP增强子反义c-fms与肝癌的研究

■Expression and relationship between c-met oncogene and gastric mucosal proliferation in helicobacter pylori inefected patients

c-met基因表达与胃癌增殖在幽门螺杆菌感染中的关系

■Increased expression of proto oncogene c fos plays an important role in the occurence and development of fibrous dysplasia.

c?fos 癌基因的过度表达在骨纤维结构不良的发生发展中起重要作用。

■STUDY ON PATHOLOGY OF GASTRIC MUCOSA AND EXPRESSION OF ONCOGENE IN CAG MODEL WHICH COMBINED WITH SYNDROME AND DISEASE?

CAG证病结合模型的胃粘膜病理和癌基因表达研究?

■Expression of CEA Oncogene ras P21 and PCNA in the Process of Malignant Transformation of Colon Adenoma

CEA、rasP21和PCNA在大肠腺瘤癌变中的表达

■CML is caused by a reciprocal chromosome translocation between chromosome 9 and 22, resulting in the short Philadelphia (Ph) chromosome carrying the BCR-ABL (Breakpoint Cluster Region-Abelson Leukaemia) oncogene.

CML的分子遗传学特征是费城染色体(Philadelphia chromosome，Ph)的出现。

■THE RELATIONSHIP BETWEEN C-erbB-2 ONCOGENE PROTEIN AND CEA EXPRESSION IN BREAST TUMOR AND PROGNOSIS OF MAMMARY CANCER

C－erbB－2癌基因蛋白及CEA在乳腺肿瘤中的表达与乳腺癌预后的关系

■dbl oncogene

dbl癌基因

■DDB at the concentration of 10-4M could significantly increase the content of cAMP in Bel-7402 cells,and also suppressed the expressions of oncogene c-myc and hepatocarcinoma marker AFP gene and enhanced the anti-oncogene p53 expression.

DDB还能明显增加Bel/7402细胞环化腺苷酸（cAMP）的含量，并抑制癌基因c－myc及肝癌标志AFP基因的表达，增强了P53抑癌基因的表达。

■The Expression of Ha-ras Oncogene in Neuroblastoma of Children and Its Clinical Significance

Ha-ras癌基因蛋白在小儿神经母细胞瘤中的表达及其临床意义

■Correlation of Differentiation and Metastasis with Amplification and Expression of Her-2/neu Oncogene in Human Lung Cancer

Her-2/neu基因扩增及其蛋白表达与肺癌分化和转移的关系

■myb oncogene

MBY 癌基因

■MEM1 is an oncogene, and its upregulation influences metastatic potential.

MEM1是致癌基因，它的上调影响癌细胞转移能力。

■The miR-17-92 cluster (miR-15a, miR-16-1, miR-155, miR-17-92 cluster, miR-142) acts as an oncogene under one set of conditions and as a tumor suppressor under another.

miR-17-92簇(miR-15a,miR-16-1,miR-155,miR-17-92cluster,miR-142)是一组可能的肿瘤相关基因。

■mos oncogene

mos 癌基因

■Expression of N-ras Oncogene Products p21 Protein in Skin and Soft Tissue Neoplasmas.

N-ras基因产物p21蛋白在皮肤、软组织肿瘤中的表达

■Neutrophil gelatinase-associated lipocalin(NGAL) is a novel member of the lipocalin family and may be a new human oncogene, but the regulation mechanism of NGAL was not clear in the cancer.

NGAL(neutrophil gelatinase-associated lipocalin)是lipocalin家族的一个新成员，可能是人类的一种新癌基因，但其在肿瘤中的表达调控机制尚不清楚。

■P53 oncogene protein

P53

■Expression of P53 oncogene was detected by in situ hybridization .

P53基因异常表达采用原位杂交方法。

■Studies on Reversion of a Transformant Line and Loss of Exogenous ras Oncogene after Treatment with an Inhibitor of PARP Enzyme

PARP酶抑制剂诱导转化细胞逆转及外源ras癌基因丢失的研究

■Expression and significance of the ras oncogene product P21 gene protein in salivary adenoid cystic carcinoma and adenolymphoma

ras癌基因产物P21在涎腺腺样囊性癌与腺淋巴瘤中的表达意义

■The data indicate that rhIL 13 enhances the expression of proto oncogene c mpl in Dami Cells.

rhIL 13增强了Dami细胞原癌基因c mpl表达 ;

■The chimeric oncogene BCR/ABL and Ph chromosome,two hall marks of CML,were detected in CML derived MSCs,normal adult MSCs,CML derived hematopoietic cells and K562 cells.

RT-PCR检测CML特异性表达的BCR/ABL基因; 对正常人、CML患者的骨髓间质干细胞进行染色体分析。

■sis oncogene family

sis(癌基因)家族

■Keywords TIF3 gene;cadmium;proto oncogen;transformation;nude mouse inoculation;NIH3T3 cell;colony formation in soft agar;

TIF3基因;镉;原癌基因;细胞转化;裸鼠;NIH3T3细胞;软琼脂集落形成;

■trk oncogene

trk(TRK)癌基因

■vav oncogene

vav癌基因

■~(99m)Tc? labeling of c?myc oncogene messenger RNA antisense oligonucleotide probe

~(99m)Tc标记c-myc mRNA反义寡核苷酸探针

■a normal gene that has the potential to become an oncogene

一种有可能成为肿瘤基因的正常基因

■Effects of the Root of Panax Notoginseng on the Abnormal Expressions of Oncogene Proteins in Gastric Mucosa in the Rats with Precancerous Lesions

三七对胃癌前病变大鼠胃粘膜癌基因蛋白异常表达的影响

■At same time,the chan ges of the expression o f P53 oncogene and telomerase was were observed.

与此同时，P53表达和端粒酶活性发生变化。

■Keywords hepatitis C virus;F protein;anti-F antibody;prevalence;hepatocellular carcinoma;oncogene;anti-oncogene;

丙型肝炎病毒;F蛋白;抗-F;流行率;肝细胞癌;癌基因;抑癌基因;

■Keywords CEPO;Centrosome;Oncogene;Protein-Protein Interaction;Signal Transduction;

中心体;原癌基因;蛋白质相互作用;信号转导;

■More and more importance is attached to the correlation between centrosome abnormity and tumorigenesis,It refers to multiple genes abnormity,mainly separated into oncogene and tumor suppressor gene.

中心体异常与肿瘤发生的相关性已越来越受到人们的重视。

■PCR requires a specific DNA (or RNA) abnormality or marker, like an oncogene, in the leukemic or lymphomatous cells in order to identify residual abnormal cells.

为了识别残留的异常细胞，聚合酶链式反应需要一个特殊的DNA或RNA的畸形或标记物，在白血病细胞或淋巴瘤细胞中，如同致癌基因一样。

■Keywords Breast neoplasm;Oncogene;Antioncogene;Gene expression;Cell cycle;Human;Immunohistochemistry;

乳腺肿瘤;癌基因;抑癌基因;基因表达;细胞周期;人;免疫组织化学;

■Keywords mica;chronic atrophic gastritis;oncogene;antioncogene;anti-apoptosis gene;gene-protein;rats;

云母;萎缩性胃炎;癌基因;抑癌基因;细胞凋亡抑制基因;基因蛋白;大鼠;

■Keywords human papillomavirus;viral oncogene;genomic instability;cell proliferation and cell differentiation;

人乳头瘤病毒;病毒癌基因;基因组稳定性;增殖与分化;

■c-Ha-ras-1 Oncogene Expression in Cervical Carcinoma

人宫颈癌中c-Ha-ras-1癌基因表达的研究

■Human Cervical Cancer Oncogene

人宫颈癌基因

■Keywords human lung adenocarcinoma A549 cells;bioactive peptides of oyster;cell cycle;oncogene and tumor repressive gene;induced differentiation;

人肺腺癌A549细胞;牡蛎低分子活性肽;细胞周期;癌基因与抑癌基因;诱导分化;

■Anything from cosmic rays to radiation to diet may activate a dormant oncogene, but how remains unknown.

从宇宙射线、射到日常饮食，任何东西都可能激活一个处于静止状态下的致癌基因，但如何激活尚不为人知。